Prevalence of HCV in Pakistani Population

Prevalence of Gynaecomastia in Male Pakistani Population

Prevalence of Gynaecomastia in Male Pakistani Population

Gynaecomastia has an overall incidence of 32 to 40%.1 The highest prevalaence is found in old age and up to 65% in men.2 The breast tissue growth is dependent on the balance between the oestrogens and androgens; thus any physiological or pathological factor that can interfere with this balance, can result in gynaecomastia.2 Physiologically, it can be neonatal, pubertal or senile. Pathologically...

Genetic Polymorphism of CYP2C19 in Pakistani Population

CYP2C19 polymorphism is associated with pretreatment drug response prediction, metabolism, and disposition. Pakistan consists of a population comprising of various ethnic groups residing in different regions of the country each claiming diverse ethnic origins. The identification of CYP450 genotypic composition of these populations is therefore necessary to avoid adverse drug reactions in these ...

The Phylogeographic and Spatiotemporal Spread of HCV in Pakistani Population

Hepatitis C Virus (HCV) is the most prevalent human pathogen in Pakistan and is the major cause of liver cirrhosis and hepatocellular carcinoma in infected patients. It has shifted from being hypo-endemic to being hyper-endemic. There was no information about the origin and evolution of the local variants. Here we use newly developed phyloinformatic methods of sequence analysis to conduct the f...

prevalence of gynaecomastia in male pakistani population

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